Warren Shire is a local government area in the Orana region of New South Wales, Australia. The Shire is located adjacent to the Macquarie River and the Mitchell and Oxley Highways. The use of the area is mainly for wool and cotton growing.
The shire was formed on 1 January 1957 through the amalgamation of Marthaguy Shire with the Municipality of Warren. The shire includes the regional towns of Warren and Nevertire.